Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Prognostic impact of number of induction courses to attain complete remission in patients with acute myeloid leukemia transplanted with either a matched sibling or human leucocyte antigen 10/10 or 9/10 unrelated donor: An Acute Leukemia Working Party European Society for Blood and Marrow Transplantation study.

Loke, Justin; Labopin, Myriam; Craddock, Charles; Socié, Gérard; Gedde-Dahl, Tobias; Blaise, Didier; Forcade, Edouard; Salmenniemi, Urpu; Huynh, Anne; Versluis, Jurjen; Yakoub-Agha, Ibrahim; Labussière-Wallet, Hélène; Maertens, Johan; Passweg, Jakob; Bulabois, Claude Eric; Gabellier, Ludovic; Mielke, Stephan; Castilla-Llorente, Cristina; Deconinck, Eric; Brissot, Eolia; Nagler, Arnon; Ciceri, Fabio; Mohty, Mohamad.

Cancer ; 2024 Apr 06.

Artigo em Inglês | MEDLINE | ID: mdl-38581695

2.

Strategies to reduce relapse risk in patients undergoing allogeneic stem cell transplantation for acute myeloid leukaemia.

Kinsella, Francesca A M; Maroto, Maria A L; Loke, Justin; Craddock, Charles.

Br J Haematol ; 2024 Apr 11.

Artigo em Inglês | MEDLINE | ID: mdl-38602216

3.

Defective T-cell response to COVID-19 vaccination in acute myeloid leukaemia and myelodysplastic syndromes.

Loke, Justin; Upasani, Vinit; Gaskell, Charlotte; Fox, Sonia; Fletcher, Rachel; Thomas, Catherine; Hopkins, Louise; Kumari, Anita; Tang, Tina; Yafai, Emily; Boucher, Rebecca; Homer, Victoria; Toth, Arpad; Chan, Y L Tracey; Randall, Katie; Rider, Tom; O'Nions, Jenny; Drew, Victoria; Pillai, Arvind; Dungarwalla, Moez; Murray, Duncan; Khan, Anjum; Wandroo, Farooq; Moore, Sally; Krishnamurthy, Pramila; Huang, Ya-Wen Jessica; Knapper, Steve; Byrne, Jenny; Zhao, Rui; Craddock, Charles; Parry, Helen; Moss, Paul; Stanworth, Simon J; Lowe, David M.

Br J Haematol ; 202(3): 498-503, 2023 08.

Artigo em Inglês | MEDLINE | ID: mdl-37303189

4.

Additional cytogenetic features determine outcome in patients allografted for TP53 mutant acute myeloid leukemia.

Loke, Justin; Labopin, Myriam; Craddock, Charles; Cornelissen, Jan J; Labussière-Wallet, Hélène; Wagner-Drouet, Eva Maria; Van Gorkom, Gwendolyn; Schaap, Nicolaas P M; Kröger, Nicolaus M; Veelken, Joan Hendrik; Rovira, Montserrat; Menard, Anne Lise; Bug, Gesine; Bazarbachi, Ali; Giebel, Sebastian; Brissot, Eolia; Nagler, Arnon; Esteve, Jordi; Mohty, Mohamad.

Cancer ; 128(15): 2922-2931, 2022 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-35612815

5.

Combination romidepsin and azacitidine therapy is well tolerated and clinically active in adults with high-risk acute myeloid leukaemia ineligible for intensive chemotherapy.

Loke, Justin; Metzner, Marlen; Boucher, Rebecca; Jackson, Aimee; Hopkins, Louise; Pavlu, Jiri; Tholouli, Eleni; Drummond, Mark; Peniket, Andy; Bishop, Rebecca; Fox, Sonia; Vyas, Paresh; Craddock, Charles.

Br J Haematol ; 196(2): 368-373, 2022 01.

Artigo em Inglês | MEDLINE | ID: mdl-34490623

6.

The role of allogeneic stem cell transplantation in the management of acute myeloid leukaemia: a triumph of hope and experience.

Loke, Justin; Malladi, Ram; Moss, Paul; Craddock, Charles.

Br J Haematol ; 188(1): 129-146, 2020 01.

Artigo em Inglês | MEDLINE | ID: mdl-31823351

7.

"Priority delivery" options for gene therapy.

Loke, Justin.

Blood ; 138(17): 1511-1512, 2021 10 28.

Artigo em Inglês | MEDLINE | ID: mdl-34709381

8.

Unravelling the apoptotic machinery in CMML.

Loke, Justin; Cockerill, Peter N.

Blood ; 137(24): 3321-3322, 2021 06 17.

Artigo em Inglês | MEDLINE | ID: mdl-34137844

9.

Arginine dependence of acute myeloid leukemia blast proliferation: a novel therapeutic target.

Mussai, Francis; Egan, Sharon; Higginbotham-Jones, Joseph; Perry, Tracey; Beggs, Andrew; Odintsova, Elena; Loke, Justin; Pratt, Guy; U, Kin Pong; Lo, Anthony; Ng, Margaret; Kearns, Pamela; Cheng, Paul; De Santo, Carmela.

Blood ; 125(15): 2386-96, 2015 Apr 09.

Artigo em Inglês | MEDLINE | ID: mdl-25710880

10.

Non-pharmacological supportive-care interventions in acute myeloid leukaemia: a review of randomised controlled trials.

O'Connor, Dominic; Loke, Justin; Brown, Malcolm; Stanworth, Simon J; Young, Annie; Prue, Gillian.

Br J Haematol ; 195(1): e97-e113, 2021 10.

Artigo em Inglês | MEDLINE | ID: mdl-34159579

11.

Supportive care in the management of patients with acute myeloid leukaemia: where are the research needs?

Loke, Justin; Lowe, David M; Miller, Laura J; Morton, Suzy; Roy, Noémi B A; Sekhar, Mallika; Stanworth, Simon J.

Br J Haematol ; 190(3): 311-313, 2020 08.

Artigo em Inglês | MEDLINE | ID: mdl-32378733

12.

Azacitidine augments expansion of regulatory T cells after allogeneic stem cell transplantation in patients with acute myeloid leukemia (AML).

Goodyear, Oliver C; Dennis, Mike; Jilani, Nadira Y; Loke, Justin; Siddique, Shamyla; Ryan, Gordon; Nunnick, Jane; Khanum, Rahela; Raghavan, Manoj; Cook, Mark; Snowden, John A; Griffiths, Mike; Russell, Nigel; Yin, John; Crawley, Charles; Cook, Gordon; Vyas, Paresh; Moss, Paul; Malladi, Ram; Craddock, Charles F.

Blood ; 119(14): 3361-9, 2012 Apr 05.

Artigo em Inglês | MEDLINE | ID: mdl-22234690

13.

Posttransplant MRD and T-cell chimerism status predict outcomes in patients who received allografts for AML/MDS.

Loke, Justin; McCarthy, Nicholas; Jackson, Aimee; Siddique, Shamyla; Hodgkinson, Andrea; Mason, John; Crawley, Charles; Gilleece, Maria; Peniket, Andrew; Protheroe, Rachel; Salim, Rahuman; Tholouli, Eleni; Wilson, Keith; Andrew, Georgia; Dillon, Richard; Khan, Naeem; Potter, Victoria; Krishnamurthy, Pramila; Craddock, Charles; Freeman, Sylvie.

Blood Adv ; 7(14): 3666-3676, 2023 07 25.

Artigo em Inglês | MEDLINE | ID: mdl-37058448

14.

Optimizing Transplant Approaches and Post-Transplant Strategies for Patients With Acute Myeloid Leukemia.

Loke, Justin; Vyas, Hrushikesh; Craddock, Charles.

Front Oncol ; 11: 666091, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-33937080

15.

Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia: Who, When, and How?

Loke, Justin; Buka, Richard; Craddock, Charles.

Front Immunol ; 12: 659595, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-34012445

16.

Augmented Reduced-Intensity Regimen Does Not Improve Postallogeneic Transplant Outcomes in Acute Myeloid Leukemia.

Craddock, Charles; Jackson, Aimee; Loke, Justin; Siddique, Shamyla; Hodgkinson, Andrea; Mason, John; Andrew, Georgia; Nagra, Sandeep; Malladi, Ram; Peniket, Andrew; Gilleece, Maria; Salim, Rahuman; Tholouli, Eleni; Potter, Victoria; Crawley, Charles; Wheatley, Keith; Protheroe, Rachel; Vyas, Paresh; Hunter, Ann; Parker, Anne; Wilson, Keith; Pavlu, Jiri; Byrne, Jenny; Dillon, Richard; Khan, Naeem; McCarthy, Nicholas; Freeman, Sylvie D.

J Clin Oncol ; 39(7): 768-778, 2021 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-33373276

17.

Subtype-specific regulatory network rewiring in acute myeloid leukemia.

Assi, Salam A; Imperato, Maria Rosaria; Coleman, Daniel J L; Pickin, Anna; Potluri, Sandeep; Ptasinska, Anetta; Chin, Paulynn Suyin; Blair, Helen; Cauchy, Pierre; James, Sally R; Zacarias-Cabeza, Joaquin; Gilding, L Niall; Beggs, Andrew; Clokie, Sam; Loke, Justin C; Jenkin, Phil; Uddin, Ash; Delwel, Ruud; Richards, Stephen J; Raghavan, Manoj; Griffiths, Michael J; Heidenreich, Olaf; Cockerill, Peter N; Bonifer, Constanze.

Nat Genet ; 51(1): 151-162, 2019 01.

Artigo em Inglês | MEDLINE | ID: mdl-30420649

18.

Donor and recipient CMV serostatus and antigenemia after renal transplantation: an analysis of 486 patients.

Hughes, David; Hafferty, John; Fulton, Lee; Friend, Peter; Devaney, Andrea; Loke, Justin; Welsh, Ken I; Handa, Ashok; Klenerman, Paul.

J Clin Virol ; 41(2): 92-5, 2008 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-18032098

19.

C/EBPα overrides epigenetic reprogramming by oncogenic transcription factors in acute myeloid leukemia.

Loke, Justin; Chin, Paulynn Suyin; Keane, Peter; Pickin, Anna; Assi, Salam A; Ptasinska, Anetta; Imperato, Maria Rosaria; Cockerill, Peter N; Bonifer, Constanze.

Blood Adv ; 2(3): 271-284, 2018 02 13.

Artigo em Inglês | MEDLINE | ID: mdl-29431622

20.

Identification of Glycopeptides as Posttranslationally Modified Neoantigens in Leukemia.

Malaker, Stacy A; Penny, Sarah A; Steadman, Lora G; Myers, Paisley T; Loke, Justin C; Raghavan, Manoj; Bai, Dina L; Shabanowitz, Jeffrey; Hunt, Donald F; Cobbold, Mark.

Cancer Immunol Res ; 5(5): 376-384, 2017 05.

Artigo em Inglês | MEDLINE | ID: mdl-28314751

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